3 Novembre 2026

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2026Altra ricercaTesto disponibile

Mitochondrial Reprogramming Along the Gut-Brain Axis in Chemotherapy-Induced Cognitive Impairment: A Narrative Review.

Amisha Malhotra, Gayathri M Rao, Aradhana Marathe et al.Oxidative medicine and cellular longevity

Chemotherapy-induced cognitive impairment (CICI), often referred to as "chemobrain," is a frequently persistent complication that significantly affects memory, attention, executive function, and overall quality of life among cancer survivors. Although mitochondrial dysfunction, oxidative stress, neuroinflammation, and gut microbiota dysbiosis have each been implicated…

2026Altra ricercaTesto disponibile

A canonical microcircuit for estimating Excitation/Inhibition (E/I) balance.

Daniel J Hauke, Julia Rodriguez-Sanchez, Hope Oloye et al.Translational psychiatry

Excitation/inhibition (E/I) balance is crucial for maintaining healthy brain function and can be disrupted in various neurological and psychiatric disorders. Despite its importance, there are few tools to study E/I balance non-invasively in humans. Here, we propose a canonical microcircuit model to estimate…

2026Caso clinicoTesto disponibile

Medically refractory epilepsy comorbid with psychogenic non-epileptic seizures and intellectual disability in a patient with balanced t(14;X) translocation: a case report.

Henry Y Feng, Ping LiJournal of medical case reports

BACKGROUND: Epilepsy affects over 50 million people worldwide, and approximately 30% of cases are treatment-resistant. Neuromodulatory therapies such as vagus nerve stimulation (VNS) and deep brain stimulation (DBS) of the anterior thalamic nuclei can reduce seizure frequency in these patients but carry risks…