3 Novembre 2026

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2026Studio osservazionaleTesto disponibile

Oral Esketamine Maintenance Treatment for Treatment-Resistant Depression: Clinical Outcomes During an Off-Label Treatment Program.

Sanne Y Smith-Apeldoorn, Jolien K E Veraart, Jan Spijker et al.Depression and anxiety

Ketamine and esketamine maintenance treatment show promise in maintaining initial antidepressant effects, yet further research is needed to optimize long-term outcomes. This observational study aimed to assess long-term depression symptom severity, safety, and tolerability in a cohort of patients receiving at-home oral esketamine…

2026Studio randomizzatoTesto disponibile

Transdiagnostic metacognitive therapy compared to disorder-specific cognitive behavioral therapy for anxiety disorders: a study protocol for a randomized controlled superiority trial

Nathalie Petersén, Fredrik Santoft, Nitya Jayaram‐Lindström et al.Trials

Abstract Background Anxiety disorders are highly prevalent worldwide and are associated with functional impairment, reduced quality of life and high societal costs. With only approximately 50% of patients achieving remission following cognitive behavioral therapy (CBT), the evaluation of other effective treatments is warranted.…