5 Novembre 2026

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2026Altra ricercaTesto disponibile

What Is Precision Psychotherapy?

Kind A, Benjamin Fink S, Walter HThe Journal of medicine and philosophy

Precision medicine impacts virtually all medical specializations, including psychiatry. Although precision psychiatry, in general, is a flourishing area of research and debate, psychotherapy as one pillar of psychiatry receives little attention. Theoretical discussions about precision psychotherapy are rare; research on precision in psychotherapy…

2026Studio randomizzatoTesto disponibile

Functional electrical stimulation for major depressive disorder: Protocol for a pilot randomized controlled trial.

Fatemeh Gholamali Nezhad, Haochen Yu, Ilya Demchenko et al.PloS one

BACKGROUND: Conventional treatments for major depressive disorder (MDD) fail to benefit one-third of patients, underscoring the need for therapies with novel mechanisms of action. Bilateral functional electrical stimulation (FES) of the facial muscles uses electrical currents to activate the muscles involved in facial…

2026Studio osservazionaleTesto disponibile

Internet-Delivered Cognitive Behavioral Therapy for Social Anxiety Disorder: Nationwide Retrospective Cohort Observational Study.

Anna Paula Laizane, Ville Ritola, Tom H Rosenström et al.Journal of medical Internet research

BACKGROUND: Internet-delivered cognitive behavioral therapies (iCBTs) can address the accessibility and affordability limitations of conventional therapy. Although iCBTs for social anxiety disorder (SAD) are efficacious, their effectiveness in routine care remains less well established. Helsinki University Hospital (HUS) provides a novel nationwide iCBT…

2026Altra ricercaTesto disponibile

Selective interoception impairments and treatment effects in borderline personality disorder.

Jella Voelter, Danilo Postin, Christina Müller et al.Translational psychiatry

Patients with borderline personality disorder (BPD) suffer from severe emotional dysregulation and disturbances in body image and self-perception. Interoception, the processing and perception of internal body signals, is closely linked to emotional processing, but it remains unclear whether BPD impairs specific interoceptive facets…

2026Altra ricercaTesto disponibile

Spatial covariance of mGluR5 density and structural degeneration in behavioral variant frontotemporal degeneration.

Melanie A Matyi, Maggie K Pecsok, Christopher A Olm et al.Imaging neuroscience (Cambridge, Mass.)

Post-mortem human brain tissue and in vivo imaging studies of behavioral variant frontotemporal degeneration (bvFTD) suggest that metabotropic glutamate receptors (mGluR) may be vulnerable to the disease process. However, these studies lack evidence demonstrating how loss of mGluR relates to clinical features of…

2026Studio osservazionaleTesto disponibile

Association of Herpes Simplex Virus Type-1 With Dementia Outcomes: Longitudinal Retrospective Cohort Study Using Real-World Electronic Health Record Data.

Muhammad Muinul Islam, Randi Foraker, Md Saber Hossain et al.JMIR formative research

BACKGROUND: Global dementia cases, currently exceeding 55 million, are projected to triple by 2050. In the absence of disease-modifying therapies, identifying modifiable risk factors is critical. Preclinical studies show that herpes simplex virus type-1 (HSV-1) is neurotropic and can drive amyloid-beta accumulation and…

2026Altra ricercaTesto disponibile

Therapist Skepticism and Adaptation to Teletherapy Under Enforced Uptake, With Theoretical Considerations for AI-Mediated Care: Qualitative Study.

Lois Ann Parri, Robin Lau, Karen AddyJMIR formative research

BACKGROUND: Mental health care is undergoing rapid digital transformation, with continued development and implementation of digitally delivered interventions. Despite growing evidence for digital mental health interventions, implementation in routine practice has often lagged technological advances. Although teletherapy became more widely accepted during the…

2026Altra ricercaTesto disponibile

The Effectiveness of Digital Intervention on Psychological Resilience in Postoperative Breast Cancer Patients During Chemotherapy Intervals: Quasi-Experimental Study.

Xin He, Qianyu Zhang, Liping Wang et al.Journal of medical Internet research

BACKGROUND: Patients with breast cancer during postoperative chemotherapy intervals commonly experience psychological distress and reduced resilience while recovering at home. Digital mindfulness interventions may provide accessible psychological support during this vulnerable period; however, evidence regarding tailored interventions for postoperative patients with breast cancer…

2026MetanalisiTesto disponibile

Effectiveness of Wearable Digital Therapeutics in Improving Sleep Outcomes Among Individuals With Insomnia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Wenhui Zhu, Mingming Chen, Yixuan Guo et al.Journal of medical Internet research

BACKGROUND: Wearable devices are increasingly used for sleep monitoring and as adjunctive treatment. Existing meta-analyses mostly pool composite digital therapies and rarely isolate stand-alone wearables or distinguish between objective and subjective end points. Whether stand-alone wearable interventions improve sleep outcomes in adults with…

2026Altra ricercaTesto disponibile

Improving Digital Measurement-Based Care Within Emerging Adult Mental Health Care Pathways: Protocol for a Co-Design Phase Embedded in a Multimethod Rapid Learning Health System Study.

Geneca Henry, Courtney Habina, Leanne Stamp et al.JMIR research protocols

BACKGROUND: Emerging adults (EAs), typically ranging from 18 to 29 years, navigate a transitional period marked by rapid developmental, social, and psychological change. Despite heightened vulnerability to mental health (MH) concerns during this stage, service systems are often fragmented, with gaps between adolescent…