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Grit Dimensions, Obsessive-Compulsive Symptomatology, and Psychological Distress: A Cross-Sectional Comparison of Two Directional Mediation Models.

Hoffman KL, Galindo-Aldana GM, García-Torres E et al.Brain sciences

Background: Mental health research has been increasingly oriented toward understanding how protective factors buffer psychological distress and support emotional stability, but the mechanisms underlying goal-oriented behavior remain less studied. One of those mechanisms is Grit, defined as a concept with two dimensions: Consistency…

Understanding veteran perspectives surrounding implantable cardioverter- defibrillator decision-making.

Stage GC, Lee M, Beltran JI et al.American heart journal plus : cardiology research and practice

Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut-brain axis modulation.

Gao R, Pu W, Lv Y et al.Frontiers in immunology

IntroductionDepression is associated with dysregulation of neuroendocrine, immune, and gut -brain axis pathways. Exercise is an effective non-pharmacological intervention; however, poor motivation and fatigue limit adherence in patients with depression.MethodsWe investigated a novel passive exercise modality, low-frequency passive vertical oscillation assisted by elastic…

Mayonnaise intake and depression: dose-response in humans and neurobehavioral and molecular mechanisms in zebrafish.

Yao Z, Dong X, Liu X et al.Biochemistry and biophysics reports

A "growth mindset of mental health" intervention increases the likelihood of initiating self-help on a mental health app: a randomized controlled trial.

Toh SHY, Horberg EJ, Kosasih FR et al.NPJ digital medicine

Mental health apps hold potential to improve access to treatment, but engagement remains low. One barrier may be the belief that mental health cannot be meaningfully improved. In a randomized controlled trial (N = 252), we examined whether a brief growth-mindset-of-mental-health intervention-portraying mental…

From Insulin Resistance to Mitochondrial Failure: A Staged Model of Impaired Metabolic Flexibility in Schizophrenia.

Myles Cubitt, Bart Ellenbroek, Anne M HaaseBiomolecules

Schizophrenia is a highly heritable neuropsychiatric disorder whose pathophysiology remains poorly understood. While neurotransmitter, neurodevelopmental, synaptic, and dysconnectivity hypotheses explain important aspects of the disorder, growing evidence suggests that metabolic dysfunction also plays a central role. This narrative review synthesises evidence from genetics,…

Longitudinal Changes in Caregiver Psychological Well-Being and Infant Temperament Following Preterm Birth: From Enrollment to 12 Months Corrected Age.

Lee D, Lee NH, Kim S et al.Children (Basel, Switzerland)

Background: Advances in neonatal care have substantially improved the survival of preterm infants; however, longitudinal changes in caregiver psychological well-being and infant temperament during follow-up remain incompletely understood. This study aimed to characterize changes in caregiver psychological measures and infant temperament from enrollment…

The Therapist from Within: A Psychodynamic-Phenomenological Comparison of the Therapist's Lived Experience in Two Anxiety-Laden Psychotherapeutic Encounters.

Xenaki LABehavioral sciences (Basel, Switzerland)

The therapist's lived experience remains comparatively underrepresented in psychotherapy research despite its importance for clinical understanding and therapeutic decision-making. Drawing on a psychodynamic-phenomenological perspective, this qualitative study examines how the therapist's experience can function as a source of clinical knowledge through the comparative…

The Relationship of Cyberchondria, Negative Affect, and Anthropometric Indices with Heart-Rate Variability Among Health Sciences Students: A Psychophysiological Study of Digital Health-Information Behavior.

Erkılıç TO, Bayraktar B, Taşci SÇBehavioral sciences (Basel, Switzerland)

BACKGROUND: We examined whether cyberchondria was associated with resting heart-rate variability (HRV) in health sciences students. METHODS: In this cross-sectional study of 600 students in Türkiye, we assessed cyberchondria using the 12-item Cyberchondria Severity Scale (CSS-12), negative affect using the 21-item Depression Anxiety…

Association of the Schizophrenia Risk Locus rs10866912 with Cerebral Volumes, Diet, and Psychosis in the UK Biobank.

Jankowski L, Periyasamy S, Youssef P et al.Genes

BACKGROUND: Leading schizophrenia GWAS signals require evaluation of their pathological significance across diverse ancestries. rs10866912 reached genome-wide significance in our Indian ancestry GWAS of schizophrenia; its risk allele reduces expression of NAPRT, the rate-limiting enzyme in the brain's principal NAD+-synthesis pathway, giving a…

Dark Empaths and Intimate Partner Violence: A Latent Profile Analysis of Dark Tetrad Traits and Empathy Dimensions in Face-to-Face and Cyber Violence Perpetration.

Galán M, Gerber N, Valls L et al.Behavioral sciences (Basel, Switzerland)

Intimate partner violence (IPV) has been consistently linked to Dark Tetrad traits (narcissism, Machiavellianism, psychopathy, and sadism), typically associated with reduced empathy. However, cognitive empathy may be used instrumentally rather than protectively, giving rise to a "dark empath" profile-elevated dark traits alongside preserved…

Emotional Expressive Flexibility and Mental Health: A Systematic Review and Meta-Analysis.

Eilert DW, Mensah PBrain sciences

Background/Objectives: The relationship between expressive flexibility-the capacity to enhance and suppress visible emotional responses according to situational demands-and mental health has not been systematically synthesized. This systematic review examined associations across psychopathology, psychological well-being, resilience and adaptive functioning, and social functioning. Methods: Following…

Enhancing Decision-Making in Pediatric Radiotherapy: Internal Validation and Expansion of the M.A.P.-RT Schedule for Sedation Need Prediction and Identification of Psychological Support Needs in a Prospective Cohort of 268 Pediatric Patients.

Marconi E, Meldolesi E, Mariani S et al.Children (Basel, Switzerland)

Background: Pediatric radiotherapy is often associated with high levels of psychological distress and vulnerability, affecting both patients and their families. In younger children, sedation is frequently required to ensure safety and adequate immobilization during treatment. The original RADAR Project demonstrated that the Multidimensional…

Depression and/or Anxiety and Health-Related Quality of Life Among Adults with Anemia: A National Analysis in the United States.

Alwhaibi MJournal of clinical medicine

Background: Anemia frequently coexists with depression and anxiety, which may further compromise health-related quality of life (HRQoL). However, limited evidence exists on the independent association of these mental health comorbidities with physical and mental HRQoL among adults with anemia. The study objective is…

The Hidden Therapeutic Bridge: Exploring Psilocybin's Role in Depression, Inflammation, and Pain - A Narrative Review.

Vazquez-Barreto M, Ugarte-Rocha M, Flores Vargas A et al.Current neuropharmacology

[Who cares for the carers ? Breaking the taboo of physicians' mental health].

Massard O, Kratzer MRevue medicale suisse

Social Media Usage Patterns and Anxiety in Chinese Adolescents: Age-Specific Risks from a Cross-Sectional Perspective.

Liu J, He R, Tie B et al.Behavioral sciences (Basel, Switzerland)

The relationship between social media use and adolescent mental health is complex and multifaceted, with recent findings suggesting that the associations vary according to the nature of social media activities, but the most common social media usage patterns among Chinese adolescents remain insufficiently…

Post-Pandemic Trends of 24-Hour Movement Behaviours and Mental Health Outcomes in Youth.

Ribeiro TD, Peralta M, Marques A et al.Children (Basel, Switzerland)

Background/Objectives: The COVID-19 pandemic disrupted youth movement behaviours and mental health, but evidence on post-pandemic trends remains limited. Therefore, this study examined differences in compliance with the 24-h movement behaviour guidelines and their association with mental health outcomes among Portuguese children and adolescents…

ADHD Presentations and Severity in Adults: Psychometric Profiles, Psychiatric Comorbidities, and Emotional Dysregulation in Relation to Psychiatric Hospitalization.

Olivola M, Landi P, Martiadis V et al.Journal of clinical medicine

Background/Objectives: Attention-deficit/hyperactivity disorder (ADHD) in adults is heterogeneous in symptom presentation, severity, and comorbid psychopathology, yet systematic data from Italian clinical populations remain limited. Methods: In this retrospective, cross-sectional study, we analyzed routine clinical data from 219 adults with a DSM-5 diagnosis of…

The effects of the arts and arts therapies on mental health outcomes of children and young people: a systematic review and meta-analysis.

Cheung PS, Rhodes S, Bahr E et al.EClinicalMedicine