3 Novembre 2026

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2026Altra ricercaTesto disponibile

Retinal layer structure on optical coherence tomography in post-traumatic stress disorder.

Sejal D Patel, Naveen Karthik, Grant A Justin et al.PloS one

PURPOSE: To assess individual retinal layer thickness and volume changes on optical coherence tomography (OCT) in individuals with post-traumatic stress disorder (PTSD) compared to controls. METHODS: Adults ≥18 years with a PTSD diagnosis were identified. Age- and sex-matched controls (±5 years) without PTSD…

2026Altra ricercaTesto disponibile

Neurophysiological and Behavioural Effects of Combined Cannabis Concentrates and Alcohol Among People Who Regularly Use Alcohol and Cannabis.

Eleftherios M Hetelekides, Patricia L Davies, Mark A Prince et al.Addiction biology

Increasingly potent concentrated cannabis products containing high levels of Δ9-tetrahydrocannabinol (THC) are being consumed with alcohol. This combination is known to acutely impair cognitive and psychomotor abilities, although few studies have evaluated alcohol and cannabis co-use using neural measures. This naturalistic feasibility study…

2026Altra ricercaTesto disponibile

Alzheimer's genetic risk factor CASS4 controls microglial focal adhesion biology and amyloidosis.

Adeline E Walsh, Benjamin A Davis, Joshua D Samuels et al.The Journal of experimental medicine

Recent genome-wide association studies have identified numerous Alzheimer's disease (AD) risk genes enriched in microglia, including Crk-associated substrate (Cas) scaffold protein family member 4 (CASS4), which encodes the adaptor protein CASS4. Despite its strong genetic association with AD, the role of CASS4 in…

2026Altra ricercaTesto disponibile

Interventions for mental health and substance use in brain injury populations: systematic evidence map and review with interactive data visualization.

Kennedy CJ, Zhao Y, Kurkimaki S et al.Frontiers in digital health

BackgroundBrain injury, mental health and substance use disorders are leading causes of death and disability worldwide. Despite high rates of comorbidity, it remains unclear how to best support individuals with concurrent brain injury and mental health or substance use problems. The objectives of…

2026Altra ricercaTesto disponibile

Anxiety and Depression in Women's Cardiovascular Health: Risk Modifiers, Mechanisms and Clinical Implications.

Granata LG, Giubilato S, Giuffrida C et al.Journal of cardiovascular development and disease

Cardiovascular disease is the leading cause of death in women, yet prevention and management have historically relied on male-centered models. Sex and gender critically influence risk, clinical presentation, and outcomes. Depression, anxiety, and psychosocial stress, more prevalent in women, act as key amplifiers…