Postnatal depression-associated breastmilk extracellular vesicles mediate intergenerational effects on offspring neurodevelopment.

Zexu Wei; Ranran Yu; Junnan Xu; Chenyu Tao; Aixia Zhang; Longjie Li; Xiaoshan Zhang; Jin He; Jiajun Yu; Xuhuang Xiao; Jiahui Guo; Tong Wang; Wei Gong; Yanbo Wang; Chen-Yu Zhang; Dijun Chen; Zhang-Peng Chen; Chenbo Ji; Xi Chen

doi:10.1016/j.cmet.2026.09.023

SCHEDA SCIENTIFICA2026Altra ricerca

Postnatal depression-associated breastmilk extracellular vesicles mediate intergenerational effects on offspring neurodevelopment.

Zexu Wei, Ranran Yu, Junnan Xu, Chenyu Tao, Aixia Zhang, Longjie Li, Xiaoshan Zhang, Jin He, Jiajun Yu, Xuhuang Xiao, Jiahui Guo, Tong Wang, Wei Gong, Yanbo Wang, Chen-Yu Zhang, Dijun Chen, Zhang-Peng Chen, Chenbo Ji, Xi Chen

Cell metabolism · 2026

Psicopatologia Neuroscienze Psicologia cognitiva Psicologia dello sviluppo

Abstract e pubblicazione originale

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Parole chiave

breastmilkhippocampal dentate gyrusintergenerational transmissionmGluR8miRNApostnatal depressionsmall extracellular vesiclesupramammillary nucleusPostnatal DepressionIntergenerational TransmissionBreastmilkHippocampal Dentate GyrusSupramammillary NucleusMglur8Small Extracellular Vesicle

Come citare questo studio

Zexu Wei, Ranran Yu, Junnan Xu, Chenyu Tao, Aixia Zhang, Longjie Li, Xiaoshan Zhang, Jin He, Jiajun Yu, Xuhuang Xiao, Jiahui Guo, Tong Wang, Wei Gong, Yanbo Wang, Chen-Yu Zhang, Dijun Chen, Zhang-Peng Chen, Chenbo Ji, Xi Chen. (2026). Postnatal depression-associated breastmilk extracellular vesicles mediate intergenerational effects on offspring neurodevelopment.. Cell metabolism. DOI: 10.1016/j.cmet.2026.09.023

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