8 Novembre 2026

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2026Altra ricercaTesto disponibile

Peptides and Peptide Analogues Targeting Acetylcholinesterase-Associated Mechanisms in Alzheimer's Disease and Dementias: Evidence Gaps, Design Strategies, and Translational Perspectives.

Joanna Zdunek, Błażej GrodnerInternational journal of molecular sciences

Alzheimer's disease and related dementias involve interacting disturbances in amyloid-β, tau, neuroinflammation, oxidative stress, mitochondrial function, synaptic integrity, and cholinergic neurotransmission. Acetylcholinesterase, in addition to terminating cholinergic signalling through acetylcholine hydrolysis, participates in non-catalytic interactions associated with amyloid-β, providing a mechanistic rationale for…

2026Studio osservazionaleTesto disponibile

Cord Blood 3-Epi-25-Hydroxyvitamin D3 and Autism-Related Cognitive Traits at Age 10 Years: An Exploratory Secondary Analysis of the KLOTHO Birth Cohort.

Spyridon N Karras, Dimitrios G Goulis, Maria Dalamaga et al.Nutrients

BACKGROUND: The C3 epimer of 25-hydroxyvitamin D3 [3-epi-25(OH)D3] can be measured in maternal and umbilical cord circulation, but whether it is related to later neurodevelopment is unknown. OBJECTIVE: To explore associations between cord 3-epi-25(OH)D3 and parent-reported autism-related trait domains at 10 years in…

2026Altra ricercaTesto disponibile

Alpiniae oxyphyllae Fructus in Alzheimer's Disease: Multi-Target Mechanisms, Current Evidence, and Future AI-Driven Perspectives.

Qihan Qin, Qingmin Yan, Keyi Zhu et al.Molecules (Basel, Switzerland)

Alpiniae oxyphyllae Fructus (Zingiberaceae; Alpinia oxyphylla Miq) (AOF) is a traditional Chinese medicinal and edible homologous material rich in bioactive metabolites, including flavonoids, terpenes, and sesquiterpenes. Its multiple metabolites and multi-target nature confer unique advantages for cognitive function and neuroprotection. However, recent advances…

2026Revisione sistematicaTesto disponibile

Cognitive Biases and Moral-Regulatory Mechanisms in White-Collar Crime: A Systematic Review and Bibliometric Mapping of Psychological Pathways to Corporate and Financial Misconduct.

Dote-Pardo J, Severino-González P, Quezada-Baier C et al.Behavioral sciences (Basel, Switzerland)

Background: White-collar crime causes major economic and social harm, yet research on its psychological mechanisms remains fragmented across criminology, behavioral ethics, accounting and finance. Objective: To synthesize research on cognitive biases and moral-regulatory mechanisms underlying white-collar, corporate and financial misconduct, and to examine…

2026Studio osservazionaleTesto disponibile

Psychological, Sociodemographic, and Lifestyle Correlates of Anxiety in Romanian Medical and Nursing Students: A Cross-Sectional Study.

Pleșea-Condratovici C, Vlase CM, Vasile IS et al.Healthcare (Basel, Switzerland)

Introduction: Anxiety is highly prevalent among health-sciences students, yet the relative strength of its sociodemographic, social-contextual, and psychological correlates is rarely examined within a single sample. This cross-sectional study examined the associations of these domains with anxiety in Romanian medical and nursing students…

2026Studio osservazionaleTesto disponibile

Prognostic Nutritional Index, Circulating Bacterial and Viral DNA, and Neurocognitive Vulnerability in Geriatric Inpatients: A Cross-Sectional Study.

Gretta Veronica Badillo Pazmay, Patrizia D'Aquila, Carlo Fortunato et al.Nutrients

BACKGROUND/OBJECTIVES: Impaired immunonutritional status is common among hospitalized older adults and may contribute to adverse outcomes through alterations in gut-brain axis pathways involving immune, microbial, and inflammatory mechanisms. The Prognostic Nutritional Index (PNI), a composite marker based on serum albumin and lymphocyte count,…

2026Altra ricercaTesto disponibile

Association Between Gray Matter Microstructure and Glucose Metabolism in Older Adults With Cognitive Decline: A Multimodal Imaging Study.

Antonietta Canna, Alessandro Pasquale De Rosa, Emanuele Nicolai et al.Human brain mapping

Cortical glucose hypometabolism is a well-established early marker of neurodegeneration in dementia, mainly reflecting neuronal and synaptic dysfunction. Its relationship with underlying microstructural alterations remains unclear. Here, we combined multi-shell diffusion microstructural and [18F]-FDG PET data to investigate the possible association between regional…

2026Altra ricercaTesto disponibile

Life Satisfaction, Hopelessness, and Attitudes Toward Irregular Migration Among Young Adults: The Moderating Role of Risk-Taking.

Odunjo-Saka KA, Nweke GEBehavioral sciences (Basel, Switzerland)

Migration is an inevitable aspect of human existence, but youth attitudes toward irregular migration have recently become a growing concern among policymakers, researchers, and government officials in developing countries like Nigeria, where challenging living conditions and lack of opportunities to achieve an individual's…

2026Altra ricercaTesto disponibile

Does Psychological Quality Matter? A Moderated Model of Family Screen Exposure and Academic Burnout Among Early Adolescents.

Yong H, Yan X, Sun L et al.Behavioral sciences (Basel, Switzerland)

Drawing on Conservation of Resources (COR) theory, this study examined whether psychological quality and its three dimensions condition the association between problematic family screen use and academic burnout among early adolescents, and whether the wider sampling setting further conditions this association. A total…