3 Novembre 2026

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2026Altra ricercaTesto disponibile

Mitochondrial Reprogramming Along the Gut-Brain Axis in Chemotherapy-Induced Cognitive Impairment: A Narrative Review.

Amisha Malhotra, Gayathri M Rao, Aradhana Marathe et al.Oxidative medicine and cellular longevity

Chemotherapy-induced cognitive impairment (CICI), often referred to as "chemobrain," is a frequently persistent complication that significantly affects memory, attention, executive function, and overall quality of life among cancer survivors. Although mitochondrial dysfunction, oxidative stress, neuroinflammation, and gut microbiota dysbiosis have each been implicated…

2026Studio osservazionaleTesto disponibile

Development and temporal validation of a screening-based prediction model for suicidal ideation at first contact with university counseling services.

Yamada Y, Ishitsuka M, Ohmachi T et al.BMC psychology

BACKGROUND: Suicidal ideation among university students is a major public health concern. Yet counseling services still lack practical tools that can identify students at elevated risk during their first clinical contact. This study aimed to develop and temporally validate a screening‑based prediction model…

2026Altra ricercaTesto disponibile

Plasma exosomal microRNA profiles associated with agitation symptoms in schizophrenia.

Yucheng Ling, Yifan Wang, Ruiqiu Zhu et al.BMC psychiatry

BACKGROUND: Inflammatory dysregulation and synaptic dysfunction have been implicated in the pathophysiology of agitation in schizophrenia (SZ), but the underlying molecular mechanisms remain unclear. Plasma exosomal microRNAs (miRNAs) are stable circulating molecules that may reflect disease-related molecular alterations associated with schizophrenia. This study…

2026Altra ricercaTesto disponibile

A canonical microcircuit for estimating Excitation/Inhibition (E/I) balance.

Daniel J Hauke, Julia Rodriguez-Sanchez, Hope Oloye et al.Translational psychiatry

Excitation/inhibition (E/I) balance is crucial for maintaining healthy brain function and can be disrupted in various neurological and psychiatric disorders. Despite its importance, there are few tools to study E/I balance non-invasively in humans. Here, we propose a canonical microcircuit model to estimate…