Sparse neuronal C4 elevation induces network-wide transcriptomic and lipid-droplet remodeling in the cortical microenvironment.

Marta Sánchez-Carbonell; Sonia Bolshakova; Juan E Ávila-Pagán; Yaseer A Sabir; Clay Griffin-Derr; Dominik G Stich; Sofia V Cieslewicz; Sheyla Esther Carmen Sifuentes; Rhushikesh A Phadke; Alison Brack; Anna Hasche-Kluender; Paige Caley; Caroline Dias; Alberto Cruz-Martín

doi:10.1371/journal.pcbi.1014871

SCHEDA SCIENTIFICA2026Altra ricerca

Sparse neuronal C4 elevation induces network-wide transcriptomic and lipid-droplet remodeling in the cortical microenvironment.

Marta Sánchez-Carbonell, Sonia Bolshakova, Juan E Ávila-Pagán, Yaseer A Sabir, Clay Griffin-Derr, Dominik G Stich, Sofia V Cieslewicz, Sheyla Esther Carmen Sifuentes, Rhushikesh A Phadke, Alison Brack, Anna Hasche-Kluender, Paige Caley, Caroline Dias, Alberto Cruz-Martín

PLoS computational biology · 2026

Psicopatologia Neuroscienze

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Parole chiave

AnimalsMiceNeuronsTranscriptomeComplement C4Lipid DropletsPrefrontal CortexFemaleSchizophreniaCerebral CortexComputational Biology

Come citare questo studio

Marta Sánchez-Carbonell, Sonia Bolshakova, Juan E Ávila-Pagán, Yaseer A Sabir, Clay Griffin-Derr, Dominik G Stich, Sofia V Cieslewicz, Sheyla Esther Carmen Sifuentes, Rhushikesh A Phadke, Alison Brack, Anna Hasche-Kluender, Paige Caley, Caroline Dias, Alberto Cruz-Martín. (2026). Sparse neuronal C4 elevation induces network-wide transcriptomic and lipid-droplet remodeling in the cortical microenvironment.. PLoS computational biology. DOI: 10.1371/journal.pcbi.1014871

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