Optimization and Metabolomic Profiling of Wolffia globosa Extract Reveal Multitarget Neuroprotective Activity Against Alzheimer's Disease with In Vitro, In Silico, and In Vivo Validation.
International journal of molecular sciences · 2026
Abstract e pubblicazione originale
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AnimalsPlant ExtractsAlzheimer DiseaseNeuroprotective AgentsMolecular Docking SimulationMetabolomicsHumansDrosophila melanogasterFabaceaeAmyloid Precursor Protein SecretasesAntioxidantsFlavonoidsAcetylcholinesteraseCholinesterase InhibitorsAspartic Acid EndopeptidasesComputer SimulationPhenolsWolffia globosaantioxidantsdonepezilenzyme inhibitionextraction optimizationmetabolomicsmolecular dockingpolyphenolssynergism
Come citare questo studio
Piya Temviriyanukul, Woorawee Inthachat, Tanongsak Laowanitwattana, Pensiri Buacheen, Uthaiwan Suttisansanee, Pornsiri Pitchakarn. (2026). Optimization and Metabolomic Profiling of Wolffia globosa Extract Reveal Multitarget Neuroprotective Activity Against Alzheimer's Disease with In Vitro, In Silico, and In Vivo Validation.. International journal of molecular sciences. DOI: 10.3390/ijms27188266
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