miR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease.

Chih-Wei Tung; Siew Chin Chan; Yi-Ching Chen; Po-Ming Wu; Pei-Hsun Cheng; Chuan-Mu Chen; Shang-Hsun Yang

doi:10.1186/s12929-026-01292-5

SCHEDA SCIENTIFICA2026Altra ricerca

miR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease.

Chih-Wei Tung, Siew Chin Chan, Yi-Ching Chen, Po-Ming Wu, Pei-Hsun Cheng, Chuan-Mu Chen, Shang-Hsun Yang

Journal of biomedical science · 2026

Psicoterapia Neuroscienze

Abstract e pubblicazione originale

L’abstract è consultabile nella fonte originale. Non viene ripubblicato qui perché non risulta verificata una licenza compatibile.

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Parole chiave

Huntington DiseaseMicroRNAsHuntingtin ProteinHumansAnimalsMiceDNA-Binding ProteinsDNA Repair EnzymesHuntington's diseaseProtein aggregationProteomic analysisRad23bUbiquitin-proteasome systemmiR-196a

Come citare questo studio

Chih-Wei Tung, Siew Chin Chan, Yi-Ching Chen, Po-Ming Wu, Pei-Hsun Cheng, Chuan-Mu Chen, Shang-Hsun Yang. (2026). miR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease.. Journal of biomedical science. DOI: 10.1186/s12929-026-01292-5

Consulta la pubblicazione originale ↗