Microglial dynamics associate with the spatial pattern of tau deposition in early Alzheimer's disease.

Marco Öchsner; Matthias Brendel; Nicolai Franzmeier; Lena Trappmann; Mirlind Zaganjori; Ersin Ersoezlue; Carolin Kurz; Jan Haeckert; Julia Utecht; Philine Marie Schirge; Boris Papazov; Oliver Pogarell; Daniel Janowitz; Katharina Buerger; Michael Ewers; Carla Palleis; Endy Weidinger; Gloria Biechele; Sebastian Schuster; Anika Finze; Florian Eckenweber; Rainer Rupprecht; Axel Rominger; Oliver Goldhardt; Timo Grimmer; Daniel Keeser; Sophia Stoecklein; Olaf Dietrich; Peter Bartenstein; Johannes Levin; Günter Höglinger; Robert Perneczky; Boris-Stephan Rauchmann

doi:10.1186/s13195-026-02230-1

SCHEDA SCIENTIFICA2026Studio osservazionale

Microglial dynamics associate with the spatial pattern of tau deposition in early Alzheimer's disease.

Marco Öchsner, Matthias Brendel, Nicolai Franzmeier, Lena Trappmann, Mirlind Zaganjori, Ersin Ersoezlue, Carolin Kurz, Jan Haeckert, Julia Utecht, Philine Marie Schirge, Boris Papazov, Oliver Pogarell, Daniel Janowitz, Katharina Buerger, Michael Ewers, Carla Palleis, Endy Weidinger, Gloria Biechele, Sebastian Schuster, Anika Finze, Florian Eckenweber, Rainer Rupprecht, Axel Rominger, Oliver Goldhardt, Timo Grimmer, Daniel Keeser, Sophia Stoecklein, Olaf Dietrich, Peter Bartenstein, Johannes Levin, Günter Höglinger, Robert Perneczky, Boris-Stephan Rauchmann

Alzheimer's research & therapy · 2026

Psicologia clinica Neuroscienze

Abstract e pubblicazione originale

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Parole chiave

AgedFemaleHumansMaleMiddle AgedAlzheimer DiseaseAmyloid beta-PeptidesBrainLongitudinal StudiesMagnetic Resonance ImagingMicrogliaPositron-Emission TomographyProspective StudiesReceptors, GABAtau ProteinsFunctional connectivityMultimodal imagingNeuroinflammationTau pathology

Come citare questo studio

Marco Öchsner, Matthias Brendel, Nicolai Franzmeier, Lena Trappmann, Mirlind Zaganjori, Ersin Ersoezlue, Carolin Kurz, Jan Haeckert, Julia Utecht, Philine Marie Schirge, Boris Papazov, Oliver Pogarell, Daniel Janowitz, Katharina Buerger, Michael Ewers, Carla Palleis, Endy Weidinger, Gloria Biechele, Sebastian Schuster, Anika Finze, Florian Eckenweber, Rainer Rupprecht, Axel Rominger, Oliver Goldhardt, Timo Grimmer, Daniel Keeser, Sophia Stoecklein, Olaf Dietrich, Peter Bartenstein, Johannes Levin, Günter Höglinger, Robert Perneczky, Boris-Stephan Rauchmann. (2026). Microglial dynamics associate with the spatial pattern of tau deposition in early Alzheimer's disease.. Alzheimer's research & therapy. DOI: 10.1186/s13195-026-02230-1

Consulta la pubblicazione originale ↗