MFN2-associated astrocyte dysfunction contributes to neuronal hyperexcitability and depressive-like behaviors.

Feng-Xia Ma; Min Wang; Shuo-Yan Fang; Xiao-Xin Wang; Shen-Han Xu; Xin-Xin Zhao; Yu-Xiao Liu; Cong Wang; Chen Qiao; Qiu-Ling Wang; Lei Cao

doi:10.1126/sciadv.aed8795

SCHEDA SCIENTIFICA2026Altra ricerca

MFN2-associated astrocyte dysfunction contributes to neuronal hyperexcitability and depressive-like behaviors.

Feng-Xia Ma, Min Wang, Shuo-Yan Fang, Xiao-Xin Wang, Shen-Han Xu, Xin-Xin Zhao, Yu-Xiao Liu, Cong Wang, Chen Qiao, Qiu-Ling Wang, Lei Cao

Science advances · 2026

Psicopatologia Neuroscienze

Abstract e pubblicazione originale

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Parole chiave

AstrocytesAnimalsGTP PhosphohydrolasesMiceNeuronsHumansMitochondriaDepressionMaleHippocampusMitophagyMajor Depressive DisorderDisease Models, AnimalSTAT1 Transcription FactorMitochondrial DynamicsMitochondrial Proteins

Come citare questo studio

Feng-Xia Ma, Min Wang, Shuo-Yan Fang, Xiao-Xin Wang, Shen-Han Xu, Xin-Xin Zhao, Yu-Xiao Liu, Cong Wang, Chen Qiao, Qiu-Ling Wang, Lei Cao. (2026). MFN2-associated astrocyte dysfunction contributes to neuronal hyperexcitability and depressive-like behaviors.. Science advances. DOI: 10.1126/sciadv.aed8795

Consulta la pubblicazione originale ↗