Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.

Aimee K Johnson; Carol A Van Hulle; Hannah Zylstra; Kate Cronin; Kevin Johnson; Leonardo Rivera-Rivera; Richard Chappell; Rachael Wilson; Przemysław R Kac; Carey E Gleason; Henrik Zetterberg; Sterling C Johnson; Anthony P Auger; Cynthia M Carlsson

doi:10.1016/j.nbd.2026.107605

SCHEDA SCIENTIFICA2026Studio randomizzato

Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.

Aimee K Johnson, Carol A Van Hulle, Hannah Zylstra, Kate Cronin, Kevin Johnson, Leonardo Rivera-Rivera, Richard Chappell, Rachael Wilson, Przemysław R Kac, Carey E Gleason, Henrik Zetterberg, Sterling C Johnson, Anthony P Auger, Cynthia M Carlsson

Neurobiology of disease · 2026

Neuroscienze Psicologia cognitiva

Abstract e pubblicazione originale

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Parole chiave

AgedFemaleHumansMaleMiddle AgedAlzheimer DiseaseAmyloid beta-PeptidesApolipoprotein E4BiomarkersChemokine CX3CL1HeterozygoteMatrix Metalloproteinase 9Peptide Fragmentstau ProteinsAPOE ε4Alzheimer's diseaseAβ42/Aβ40CX3CL1ICAM-1InflammationMMP-9P-tau217VCAM-1

Come citare questo studio

Aimee K Johnson, Carol A Van Hulle, Hannah Zylstra, Kate Cronin, Kevin Johnson, Leonardo Rivera-Rivera, Richard Chappell, Rachael Wilson, Przemysław R Kac, Carey E Gleason, Henrik Zetterberg, Sterling C Johnson, Anthony P Auger, Cynthia M Carlsson. (2026). Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.. Neurobiology of disease. DOI: 10.1016/j.nbd.2026.107605

Consulta la pubblicazione originale ↗