Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study.

Joshua Harvey; Jennifer Imm; Morteza Kouhsar; Adam R Smith; Byron Creese; Rebecca G Smith; Gregory Wheildon; Valentin Laroche; Szi Kay Leung; Leonidas Chouliaras; Gemma Shireby; Zane Jaunmuktane; Eduardo De Pablo-Fernández; Thomas Warner; Debra J Lett; Djordje Gveric; Hannah Brooks; Johannes Attems; Alan Thomas; Wilma Dj Van de Berg; Emma Dempster; Clive Ballard; John T O'Brien; Dag Aarsland; Jonathan Mill; Lasse Pihlstrøm; Ehsan Pishva; Katie Lunnon

doi:10.1038/s41467-026-77009-x

SCHEDA SCIENTIFICA2026Metanalisi

Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study.

Joshua Harvey, Jennifer Imm, Morteza Kouhsar, Adam R Smith, Byron Creese, Rebecca G Smith, Gregory Wheildon, Valentin Laroche, Szi Kay Leung, Leonidas Chouliaras, Gemma Shireby, Zane Jaunmuktane, Eduardo De Pablo-Fernández, Thomas Warner, Debra J Lett, Djordje Gveric, Hannah Brooks, Johannes Attems, Alan Thomas, Wilma Dj Van de Berg, Emma Dempster, Clive Ballard, John T O'Brien, Dag Aarsland, Jonathan Mill, Lasse Pihlstrøm, Ehsan Pishva, Katie Lunnon

Nature communications · 2026

Neuroscienze

Abstract e pubblicazione originale

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Parole chiave

DNA MethylationHumansGenome-Wide Association StudyLewy Body DiseaseQuantitative Trait Locialpha-SynucleinBrainLewy BodiesParkinson DiseaseEpigenesis, GeneticCohort StudiesGenetic Predisposition to Disease

Come citare questo studio

Joshua Harvey, Jennifer Imm, Morteza Kouhsar, Adam R Smith, Byron Creese, Rebecca G Smith, Gregory Wheildon, Valentin Laroche, Szi Kay Leung, Leonidas Chouliaras, Gemma Shireby, Zane Jaunmuktane, Eduardo De Pablo-Fernández, Thomas Warner, Debra J Lett, Djordje Gveric, Hannah Brooks, Johannes Attems, Alan Thomas, Wilma Dj Van de Berg, Emma Dempster, Clive Ballard, John T O'Brien, Dag Aarsland, Jonathan Mill, Lasse Pihlstrøm, Ehsan Pishva, Katie Lunnon. (2026). Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study.. Nature communications. DOI: 10.1038/s41467-026-77009-x

Consulta la pubblicazione originale ↗