Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants.

Kristina Shkirkova; Naomi S Sta Maria; Herbert Anson; Yashar Aghaei; Mohammad Mahdi Badami; Ararat Chakhoyan; Jose A Godoy-Lugo; Claire Chung; Salma Durra; Angela Tang-Tan; Lifu Zhao; Alexandra Demetriou; Manuel Morales; Sindhu Daggupati; Isabella Bent; Hyoungjin Park; Caleb Franklin; Selena Chen; Giovanni Chahine; Skyye Dodds-Lewis; Masako Morishita; Russell E Jacobs; Jean-François Gout; Wendy J Mack; Henry Jay Forman; Bérénice A Benayoun; Marc Vermulst; Mitchell D Cohen; Matthew Campen; Constantinos Sioutas; William J Mack; Caleb E Finch; Max A Thorwald

doi:10.1016/j.redox.2026.104390

SCHEDA SCIENTIFICA2026Altra ricerca

Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants.

Kristina Shkirkova, Naomi S Sta Maria, Herbert Anson, Yashar Aghaei, Mohammad Mahdi Badami, Ararat Chakhoyan, Jose A Godoy-Lugo, Claire Chung, Salma Durra, Angela Tang-Tan, Lifu Zhao, Alexandra Demetriou, Manuel Morales, Sindhu Daggupati, Isabella Bent, Hyoungjin Park, Caleb Franklin, Selena Chen, Giovanni Chahine, Skyye Dodds-Lewis, Masako Morishita, Russell E Jacobs, Jean-François Gout, Wendy J Mack, Henry Jay Forman, Bérénice A Benayoun, Marc Vermulst, Mitchell D Cohen, Matthew Campen, Constantinos Sioutas, William J Mack, Caleb E Finch, Max A Thorwald

Redox biology · 2026

Neuroscienze

Abstract e pubblicazione originale

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Parole chiave

Alzheimer DiseaseFerroptosisHumansAir PollutantsOxidative StressAmyloid beta-PeptidesAnimalsVehicle EmissionsSeptember 11 Terrorist AttacksParticulate MatterIronTranscriptomeDustAir pollutionGPx4Lipid raftsMetal neurotoxicityWhite matter vulnerability

Come citare questo studio

Kristina Shkirkova, Naomi S Sta Maria, Herbert Anson, Yashar Aghaei, Mohammad Mahdi Badami, Ararat Chakhoyan, Jose A Godoy-Lugo, Claire Chung, Salma Durra, Angela Tang-Tan, Lifu Zhao, Alexandra Demetriou, Manuel Morales, Sindhu Daggupati, Isabella Bent, Hyoungjin Park, Caleb Franklin, Selena Chen, Giovanni Chahine, Skyye Dodds-Lewis, Masako Morishita, Russell E Jacobs, Jean-François Gout, Wendy J Mack, Henry Jay Forman, Bérénice A Benayoun, Marc Vermulst, Mitchell D Cohen, Matthew Campen, Constantinos Sioutas, William J Mack, Caleb E Finch, Max A Thorwald. (2026). Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants.. Redox biology. DOI: 10.1016/j.redox.2026.104390

Consulta la pubblicazione originale ↗