HPSC-derived mesenchymal stromal cells ameliorate murine autistic-like phenotypes through activating oxytocinergic neurons.

Yinong Huang; Yixuan Liu; Yilin Liu; Hongjie Liang; Yunli Tong; Ruijie Li; Xiaoran Zhang; Yiling Wang; Yiwen Deng; Jihao Wu; Yue Shu; Qiying Lu; Yuan Qiu; Jinsi Chen; Yucheng Ba; Jiayun Fang; Jiang Hao; Weiqiang Li; Haipeng Xiao; Weijun Huang; Andy Peng Xiang

doi:10.1126/sciadv.adt4995

SCHEDA SCIENTIFICA2026Altra ricerca

HPSC-derived mesenchymal stromal cells ameliorate murine autistic-like phenotypes through activating oxytocinergic neurons.

Yinong Huang, Yixuan Liu, Yilin Liu, Hongjie Liang, Yunli Tong, Ruijie Li, Xiaoran Zhang, Yiling Wang, Yiwen Deng, Jihao Wu, Yue Shu, Qiying Lu, Yuan Qiu, Jinsi Chen, Yucheng Ba, Jiayun Fang, Jiang Hao, Weiqiang Li, Haipeng Xiao, Weijun Huang, Andy Peng Xiang

Science advances · 2026

Psicopatologia Psicologia dello sviluppo

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Parole chiave

AnimalsOxytocinMesenchymal Stem CellsNeuronsMicePhenotypeDinoprostoneDisease Models, AnimalMice, KnockoutNerve Tissue ProteinsAutistic DisorderInduced Pluripotent Stem CellsHumansParaventricular Hypothalamic NucleusAutism Spectrum DisorderMaleMicrofilament Proteins

Come citare questo studio

Yinong Huang, Yixuan Liu, Yilin Liu, Hongjie Liang, Yunli Tong, Ruijie Li, Xiaoran Zhang, Yiling Wang, Yiwen Deng, Jihao Wu, Yue Shu, Qiying Lu, Yuan Qiu, Jinsi Chen, Yucheng Ba, Jiayun Fang, Jiang Hao, Weiqiang Li, Haipeng Xiao, Weijun Huang, Andy Peng Xiang. (2026). HPSC-derived mesenchymal stromal cells ameliorate murine autistic-like phenotypes through activating oxytocinergic neurons.. Science advances. DOI: 10.1126/sciadv.adt4995

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