Gain-of-function mutation of type 2 ryanodine receptor attenuates dopaminergic neuron development associated with Ca2+ overload-triggered oxidative damage in mitochondria.
Biochemical and biophysical research communications · 2026
Abstract e pubblicazione originale
L’abstract è consultabile nella fonte originale. Non viene ripubblicato qui perché non risulta verificata una licenza compatibile.
Leggi nella fonte originale ↗Parole chiave
Ryanodine Receptor Calcium Release ChannelHumansCalciumMitochondriaOxidative StressMaleDopaminergic NeuronsGain of Function MutationPolymorphic Catecholaminergic Ventricular TachycardiaTachycardia, VentricularAutism Spectrum DisorderReactive Oxygen SpeciesNeurodevelopmentOxidative stressRyanodine receptor type 2
Come citare questo studio
Yosuke Ito, Shuangshan Dong, Hiroki Kato, Zhiyan Zhou, Lu Wang, Yuta Hirofuji, Hiroshi Sato, Pin Fee Chong, Yuichiro Hirata, Kenichiro Yamamura, Takahiro A Kato, Yasunari Sakai, Satoshi Fukumoto, Keiji Masuda. (2026). Gain-of-function mutation of type 2 ryanodine receptor attenuates dopaminergic neuron development associated with Ca2+ overload-triggered oxidative damage in mitochondria.. Biochemical and biophysical research communications. DOI: 10.1016/j.bbrc.2026.154416
Consulta la pubblicazione originale ↗