Forced treadmill running and ladder climbing physical activity attenuates cognitive decline and protein aggregates in aged 3xTg-AD mice.

Mingming Yang; Xiaosen Ouyang; Sishir Gautam; Malique Singleton; Viyaleta Davydzenka; Jianhua Zhang; Yun Li

doi:10.1186/s13041-026-01332-z

SCHEDA SCIENTIFICA2026Altra ricerca

Forced treadmill running and ladder climbing physical activity attenuates cognitive decline and protein aggregates in aged 3xTg-AD mice.

Mingming Yang, Xiaosen Ouyang, Sishir Gautam, Malique Singleton, Viyaleta Davydzenka, Jianhua Zhang, Yun Li

Molecular brain · 2026

Psicologia clinica Psicoterapia Psicologia sociale Psicologia cognitiva

Abstract e pubblicazione originale

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Parole chiave

AnimalsAlzheimer DiseaseMice, TransgenicAgingCognitive DysfunctionProtein AggregatesPhysical Conditioning, AnimalAmyloid beta-Peptidestau ProteinsHippocampusRunningGliosisSocial BehaviorMaleMaze LearningAgeAlzheimer’s diseaseAmyloid-betaBehaviorInhibitory neuronsNeuroinflammationProtein aggregates

Come citare questo studio

Mingming Yang, Xiaosen Ouyang, Sishir Gautam, Malique Singleton, Viyaleta Davydzenka, Jianhua Zhang, Yun Li. (2026). Forced treadmill running and ladder climbing physical activity attenuates cognitive decline and protein aggregates in aged 3xTg-AD mice.. Molecular brain. DOI: 10.1186/s13041-026-01332-z

Consulta la pubblicazione originale ↗