Elucidating the role of DEAF1 in neurodevelopment and shared molecular pathways in high-risk autism genes using cortical organoids.
Science advances · 2026
Abstract e pubblicazione originale
L’abstract è consultabile nella fonte originale. Non viene ripubblicato qui perché non risulta verificata una licenza compatibile.
Leggi nella fonte originale ↗Parole chiave
HumansOrganoidsNeurodevelopmentMutationDNA-Binding ProteinsTranscription FactorsWnt Signaling PathwayAutistic DisorderCell DifferentiationCerebral CortexNuclear ProteinsAutism Spectrum DisorderSignal TransductionCell Proliferation
Come citare questo studio
Jonghun Kim, Mu Seog Choe, Woo Sub Yang, Cynthia Lo, Hui-Wen Liu, Tae Hwan Kwak, Kyuhwan Na, Ferdi Ridvan Kiral, Yangfei Xiang, Caihong Qiu, Mei Zhong, Maria Lee, Yoshiaki Tanaka, Bilal Cakir, Seok Chung, In-Hyun Park. (2026). Elucidating the role of DEAF1 in neurodevelopment and shared molecular pathways in high-risk autism genes using cortical organoids.. Science advances. DOI: 10.1126/sciadv.ady5166
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