Design, Synthesis and Evaluation Donepezil-Based Dual BuChE/FAAH Inhibitors for Alzheimer's Disease Therapy.

Xiaodan Liu; Yinxin Wu; Yulu Ding; Shilin Hu; Hui Hou; Yicheng Zong; Ziwen Zhang; Wenjian Tang

doi:10.1021/acs.jmedchem.6c01848

SCHEDA SCIENTIFICA2026Altra ricerca

Design, Synthesis and Evaluation Donepezil-Based Dual BuChE/FAAH Inhibitors for Alzheimer's Disease Therapy.

Xiaodan Liu, Yinxin Wu, Yulu Ding, Shilin Hu, Hui Hou, Yicheng Zong, Ziwen Zhang, Wenjian Tang

Journal of medicinal chemistry · 2026

Psicoterapia Psicologia cognitiva

Abstract e pubblicazione originale

L’abstract è consultabile nella fonte originale. Non viene ripubblicato qui perché non risulta verificata una licenza compatibile.

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Parole chiave

Alzheimer DiseaseDonepezilAnimalsCholinesterase InhibitorsHumansButyrylcholinesteraseDrug DesignRatsMicePC12 CellsStructure-Activity RelationshipMaleAmyloid beta-PeptidesNeuroprotective AgentsAlzheimer’s diseasecholinesterase inhibitorsfatty acid amide hydrolasemulti-target directed ligandsneuroprotection

Come citare questo studio

Xiaodan Liu, Yinxin Wu, Yulu Ding, Shilin Hu, Hui Hou, Yicheng Zong, Ziwen Zhang, Wenjian Tang. (2026). Design, Synthesis and Evaluation Donepezil-Based Dual BuChE/FAAH Inhibitors for Alzheimer's Disease Therapy.. Journal of medicinal chemistry. DOI: 10.1021/acs.jmedchem.6c01848

Consulta la pubblicazione originale ↗