AUT00206, a novel and selective Kv3.1/3.2 channel modulator, restores cognitive dysfunction and negative symptoms in an animal model for schizophrenia symptomatology.
Journal of psychopharmacology (Oxford, England) · 2026
Abstract e pubblicazione originale
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Leggi nella fonte originale ↗Parole chiave
AnimalsFemaleSchizophreniaDisease Models, AnimalShaw Potassium ChannelsRatsPhencyclidineCognitive DysfunctionSocial BehaviorBehavior, AnimalRecognition, PsychologyReversal LearningCognitive EnhancementCognitionAUT00206Kv3.1/2 channel modulatorcognitionnovel object recognitionratreversal learningschizophreniasocial interactionsubchronic phencyclidine model
Come citare questo studio
Marianne Leger, Daniela Cadinu, Jennifer Fletcher, Agostino Marasco, Giuseppe Alvaro, Daniel Umbricht, Charles Large, Ben Grayson, Joanna C Neill, Michael K Harte. (2026). AUT00206, a novel and selective Kv3.1/3.2 channel modulator, restores cognitive dysfunction and negative symptoms in an animal model for schizophrenia symptomatology.. Journal of psychopharmacology (Oxford, England). DOI: 10.1177/02698811261473459
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