ARRDC4 drives Tau pathology via USP14-mediated deubiquitination and acts as a novel therapeutic target in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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AnimalsAlzheimer Diseasetau ProteinsHumansUbiquitinationUbiquitin ThiolesteraseMiceDisease Models, AnimalDrosophilaDrosophila ProteinsPhosphorylationTauopathiesARRDC4Alzheimer's diseaseTau pathologyTau propagationUSP14deubiquitinationneuroinflammationprotein quality controltauopathyubiquitination
Come citare questo studio
Jiaqi Liu, Bing-Wen Xiao, Xiaohan Mai, Yi-Chun Wang, Yiyan Fei, Yang Wang, Steven X Hou. (2026). ARRDC4 drives Tau pathology via USP14-mediated deubiquitination and acts as a novel therapeutic target in Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association. DOI: 10.1002/alz.71926
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