5 Novembre 2026

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2026Altra ricercaTesto disponibile

Supporting Video-Based Psychotherapy While Asking Who Benefits and Who Remains in Treatment.

Souza LDM, Jansen K, da Silva RAJournal of medical Internet research

UnlabelledMeyer-Keirath and colleagues found no significant difference in posttreatment symptoms between video-based and face-to-face psychotherapy. However, the wide confidence interval indicates substantial imprecision, while the prediction interval suggests that comparative effects may vary considerably across settings; neither supports a conclusion of equivalence. For…

2026Altra ricercaTesto disponibile

The Impact of Cladribine Tablets on Cognition Over One Year in Patients With Multiple Sclerosis: A Preliminary Study.

Alexis M Callen, Bonnie I Glanz, Shahamat Tauhid et al.Brain and behavior

INTRODUCTION: Cognitive impairment is common in multiple sclerosis (MS), affecting >40% of patients. Cladribine tablets are a high-efficacy MS disease-modifying therapy to prevent relapses and limit disease progression. Our previous study showed cortical gray matter lesion stability over one year after the start…

2026Altra ricercaTesto disponibile

Patient-Reported Outcomes Following Two-Tined Three-Site Conventional Radiofrequency Ablation of Genicular Nerves for Chronic Knee Pain.

Chen M, Tosun S, Thompson NR et al.Cureus

BackgroundGenicular nerve radiofrequency ablation (GNRFA) has emerged as an effective therapy for chronic knee pain. Although some studies have evaluated its effectiveness, there is limited real-world data on the long-term patient-reported outcome (PRO) data for GNRFAs.Objective This study aimed to evaluate PROs following…

2026Altra ricercaTesto disponibile

Clinical Presentation of, Treatment Approaches for, and the Impact of Social Determinants of Health on Pediatric Catatonia: A Structured Qualitative Synthesis and Targeted Literature Review.

Gonzalez R, Sekhon SS, Tedesco SCureus

Catatonia is a complex neuropsychiatric syndrome with diverse presentations, including stuporous, excited, malignant, and periodic forms. While well documented in adults, pediatric catatonia remains underrecognized, with limited literature addressing its presentation, treatment, and the influence of social determinants of health (SDOH). This structured…

2026Caso clinicoTesto disponibile

Psychotropic Polypharmacy in a 5-Year-Old Boy with a SHANK3 Variant and Complex Mental Health Problems.

Briegel W, Kunstmann EChildren (Basel, Switzerland)

BackgroundDysfunction of the SHANK3 gene has been linked to several neuropsychiatric and neurodevelopmental disorders, such as attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and epilepsy. SHANK3 haploinsufficiency is the known etiology of Phelan-McDermid syndrome.Case presentationThis report presents a five-year-old boy in whom the…