6 Novembre 2026

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2026Altra ricercaTesto disponibile

3D epigenome of glial cell types in developing human cortex.

Ian R Jones, Li Wang, Michael Kosicki et al.Nature

The human cortex is complex and heterogeneous, undergoing extensive expansion during development1,2. Our prior study of neurogenesis, including radial glia (RG), intermediate progenitor cells, excitatory neurons and interneurons demonstrated that chromatin looping underlies transcriptional regulation for lineage-specific genes, shedding light on how non-coding…

2026Studio randomizzatoTesto disponibile

Extended Long-Term Effects of Cognitive and Aerobic Training on Cognitive Function in Patients With Stress-Related Exhaustion Disorder: A 4.5-Year Follow-Up of a Randomized Controlled Trial.

Ingela Aronsson, Anna Stigsdotter Neely, Carl-Johan Boraxbekk et al.Stress and health : journal of the International Society for the Investigation of Stress

Stress-related conditions like clinical burnout and exhaustion disorder (ED) are associated with enduring cognitive problems. We have previously demonstrated that the addition of computerised cognitive training (CCT) and aerobic training (AT) to a multimodal rehabilitation programme (MMR) yielded greater improvements in cognitive function…

2026Altra ricercaTesto disponibile

Testing for Genetic Interactions in Complex Disease With Distance Correlation.

Fernando Castro-Prado, Javier Costas, Dominic Edelmann et al.Biometrical journal. Biometrische Zeitschrift

Understanding epistasis (genetic interaction) may shed some light on the genomic basis of common diseases, including disorders of maximum interest due to their high socioeconomic burden, like schizophrenia. Distance correlation is an association measure that characterizes general statistical independence between random variables, not…