3 Novembre 2026

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2026Altra ricercaTesto disponibile

Characteristic central nervous system fingerprints and related molecular signatures in difficult-to-treat rheumatoid arthritis.

Gunkl-Tóth L, Orsi G, Császár-Nagy N et al.Journal of neuroinflammation

BACKGROUND: Despite guideline-recommended treatment, approximately 30% of rheumatoid arthritis (RA) patients remain symptomatic and are classified as difficult-to-treat (D2T), representing an unmet clinical need. D2T RA is a heterogeneous state potentially involving differences across several biological and psychological levels, but the exact underlying…

2026Altra ricercaTesto disponibile

An oral-origin Streptococcus salivarius associated with schizophrenia reshapes intestinal T-cell immunity and promotes IL-17A-dominated inflammation.

Yongyong Kang, Yajuan Fan, Qingyan Ma et al.Frontiers in immunology

BACKGROUND: Emerging evidence suggests that oral microbial dysbiosis contributes to neuropsychiatric disorders through microbiome-immune interactions. We previously identified an oral-origin Streptococcus salivarius enriched in individuals with schizophrenia (SCZ) and demonstrated its ability to become enriched in the intestine after oral administration. However, whether…

2026Altra ricercaTesto disponibile

Personalized stress detection from wearable physiological signals via Digital Twin-inspired subject embeddings and recurrent neural networks.

Alharbi HFrontiers in physiology

INTRODUCTION: The rising prevalence of psychological stress and its associated adverse health effects have created an urgent need for reliable and automated detection methods that move beyond traditional self-report tools. While wearable sensing systems offer a promising avenue for continuous monitoring, current systems…