3 Novembre 2026

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2026Altra ricercaTesto disponibile

Diagnostic accuracy of a self-administered digital cognitive test battery for differentiating early Alzheimer's disease from controls.

Sophia Rutt, Paulina Tegethoff, Marleen Taute et al.European archives of psychiatry and clinical neuroscience

BACKGROUND: Paper-pencil assessments face limitations in accessibility, lengthy administration, and interrater reliability. Digital tools may overcome these by offering user-friendly, non-verbal, and scalable assessments. This study investigated the diagnostic accuracy of BraincheX, a novel digital test battery focused on accessibility and usability, by…

2026Altra ricercaTesto disponibile

Wake-activated neuronal populations that regulate sleep drive.

William Joo, Clare Diester, Vassilis Bitsikas et al.Nature

Prolonged wakefulness increases sleep drive and is normally compensated for by increased sleep1-3. This homeostatic regulation of sleep shapes our lives profoundly, but the underlying neural circuit mechanisms remain poorly understood. Here, we identify wake-activated neurons that regulate sleep drive in mice, using…