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Efficacy of A Virtual Agent-Based Digital Intervention (Echo App V2.0) for Patients With Alcohol Use Disorder: Randomized Controlled Trial.

Shuo Li, Dapeng Zhang, Weicong Sang et al.Journal of medical Internet research

BACKGROUND: Virtual agents powered by dialogue trees have emerged as promising tools to overcome limitations of text-only psychological interventions in mental health treatment. OBJECTIVE: This study evaluated whether a virtual agent-based digital psychological intervention plus treatment as usual (TAU) reduced craving and relapse…

Sexual dysfunction after female genital mutilation/cutting: A retrospective cross-sectional study of associations with organ-specific genital anatomy, trauma history, and psychiatric comorbidity.

Emily Lock, Veronica AdesPloS one

Sexual dysfunction after female genital mutilation/cutting (FGM/C) is poorly characterized, limiting targeted clinical intervention. In a concentrated FGM/C referral population, we aimed to characterize patterns of sexual dysfunction and evaluate associations with organ-specific genital anatomy, trauma history, and psychiatric comorbidities among women with…

Amyloid-beta-targeting monoclonal antibodies in early Alzheimer's disease: a cochrane review summary and appraisal for the neurological community.

Diogo Haddad Santos, Anderson Matheus Pereira da SilvaNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

BACKGROUND: Seven amyloid-beta-targeting monoclonal antibodies have been trialled in early Alzheimer's disease. They differ in epitope and in how much plaque they clear; only two have traditional approval. A 2026 Cochrane Review pooled all seven as one class. We ask what that average…

Prevalence of neuropsychiatric and seizure disorders in neurofibromatosis type 1: a systematic review and meta-analysis.

Elena Moreno-Charco, Carlos Pascual-Morena, Celia Álvarez-Bueno et al.Journal of neurology

Exosomes in Alzheimer's Disease: From Pathological Mechanisms to Biomarker Potential and Therapeutic Applications.

Arda Can AydınMolecular neurobiology

Targeting Shame and Guilt in Psychotherapy: From Conceptual Understanding to Diverse Therapeutic Approaches.

James N Kirby, Deborah LeeJournal of clinical psychology

Improving Cardiometabolic Health in Adolescent Girls With Elevated Anxiety: Web-Based Multisite, Pilot, and Feasibility Randomized Controlled Trial.

Caitlin Edwards, Lisa Ranzenhofer, Jason Lavender et al.JMIR cardio

BACKGROUND: Anxiety is common in adolescents with elevated BMI (kg/m2), affecting 33%-43% of adolescents with overweight or obesity (age- and sex-specific BMI ≥85th percentile ). Anxiety has been associated with poorer cardiometabolic health, and disinhibited eating in response to anxiety may be a…

A dual-path trust-risk model of GenAI continuance: Conversational attributes, psychological evaluations, and configurational patterns.

Binyuan Zhang, Tingting JiaActa psychologica

Cognitive, functional and psychological aging in adults with and without intellectual disability and its evolution over time with a multicomponent program: Prospective longitudinal study.

Alejandra Aguilar-Latorre, Bárbara Oliván-Blázquez, Marta Sánchez-Peña et al.Geriatric nursing (New York, N.Y.)

When physical activity becomes a personal choice: How psychological ownership in physical activity motivates sustained participation among college students.

Qing Yu, Sha LiPsychology of sport and exercise

Comparative effectiveness of multiple interventions for Alzheimer's disease on ABC syndromes and QoL: A Bayesian network meta-analysis.

Fujia Gao, Guangxin Luo, Bokuan Liu et al.iScience

Adjunctive psychobiotic Lactiplantibacillus plantarum PS128 ameliorates gastrointestinal comorbidities and alters circulating miRNAs and gut microbiota in children with Tourette syndrome: a randomized controlled trial.

Yu-Tzu Chang, Syuan-Yu Hong, Sheng-Shing Lin et al.Food & function

Continuous sliding pressure feedback enhances supernumerary robotic thumb proprioception over discrete vibrotactile feedback: behavioral and EEG evidence.

Haneen Alsuradi, Georgios Korres, Pi Ko et al.Journal of neural engineering

Paternal Valproate Exposure and Offspring Neurodevelopmental Outcomes.

Yen-Chen Anne Feng, Mei-Chen Lin, Ching-Hsuan Tseng et al.Neurology

Interleukin-17A-producing γδ T cells drive cognitive dysfunction in periodontitis.

Sari Kishikawa, Jun-Ichi Nagao, Kenji Toyonaga et al.Cell reports

Lesion-Level Subtypes of White Matter Hyperintensity Evolution Beyond Spatial Location.

Raul Gonzalez-Gomez, Enzo Tagliazuchi, Cecilia Gonzalez Campo et al.Neurology

Centrally Acting Medications, Chronic Pain, and Orthopedic Surgical History Among Former American Football Players.

Alexa Puleio, Ina Hoti, William B Barr et al.Neurology

Association Between Alzheimer Pathology, Sleep, and Cognition in Patients With Late-Onset Unexplained Epilepsy.

Rani A Sarkis, Hyun-Sik Yang, Lei Liu et al.Neurology

Longitudinal Dynamics of the Blood Proteome Within the Alzheimer Spectrum in Down Syndrome.

Olivia Wagemann, Georg S Nuebling, Katja Sandkühler et al.Neurology

Identifying shared and personalized brain functional connectivity subspace across neuropsychiatric disorders.

Shi Liu, Zhichao Wang, Yueming Wang et al.Journal of neural engineering